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báo cáo hóa học:" Arthroscopic debridement of the osteoarthritic knee combined with hyaluronic acid (Orthovisc®) treatment: A case series and review of the literature"

Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học quốc tế đề tài : Arthroscopic debridement of the osteoarthritic knee combined with hyaluronic acid (Orthovisc®) treatment: A case series and review of the literature | Journal of Orthopaedic Surgery and Research BioMed Central Research article Arthroscopic debridement of the osteoarthritic knee combined with hyaluronic acid Orthovisc treatment A case series and review of the literature Xinning Li Agam Shah Patricia Franklin Renee Merolli Jill Bradley and Brian Busconi Open Access Address University of Massachusetts Medical Center Department of Orthopaedic Surgery Division of Sports Medicine 55 Lake Avenue North Worcester MA 01655 USA Email Xinning Li - xinning.li@gmail.com Agam Shah - a111shah@yahoo.com Patricia Franklin - Patricia.Franklin@umassmed.edu Renee Merolli - merollir@ummhc.org Jill Bradley - jill.bradley@umassmed.edu Brian Busconi - busconib@ummhc.org Corresponding author Published 17 September 2008 Received 9 May 2008 Journal of Orthopaedic Surgery and Research 2008 3 43 doi l0.ll86 l749-799X-3-43 Accepted I7 September 2008 This article is available from http www.josr-online.cOm content 3 1 43 2008 Li et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Objective An evaluation of safety and efficacy of high molecular weight hyaluronan HA delivered at the time of arthroscopic debridement of the osteoarthritic knee. Methods Thirty consecutive patients who met inclusion and exclusion criteria underwent arthroscopic debridement by a single surgeon and concomitant delivery of 6 ml 90 mg HA Orthovisc . These patients were evaluated preoperatively at 6 weeks 3 and 6 months post-operatively. Evaluations consisted of WOMAC pain score SF-36 Physical Component Summary PCS score and complications. Results No complications occurred during this study. Pre-op average WOMAC pain score was 6.8 - 3.5 n 30 with a reduction to 3.4 - 3.1 at 6 weeks n 27 . Final average WOMAC pain score .