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Báo cáo hóa học: " Viable chimaeric viruses confirm the biological importance of sequence specific maize streak virus movement protein and coat protein interactions"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Viable chimaeric viruses confirm the biological importance of sequence specific maize streak virus movement protein and coat protein interactions | Virology Journal BioMed Central Open Access Viable chimaeric viruses confirm the biological importance of sequence specific maize streak virus movement protein and coat protein interactions Eric van der Walt1 Kenneth E Palmer2 3 4 Darren P Martin1 5 and Edward P Rybicki 1 5 Address Department of Molecular and Cell Biology University of Cape Town Cape Town South Africa 2James Graham Brown Cancer Center University of Louisville Louisville USA 3Department of Pharmacology and Toxicology University of Louisville Louisville USA 4Owensboro Cancer Research Program Owensboro USA and institute of Infectious Disease and Molecular Medicine University of Cape Town Cape Town South Africa Email Eric van der Walt - eric.vanderwalt@kapabiosystems.com Kenneth E Palmer - kenneth.palmer@louisville.edu Darren P Martin - darrin.martin@uct.ac.za Edward P Rybicki - ed.rybicki@uct.ac.za Corresponding author Published 20 May 2008 Received 22 April 2008 Accepted 20 May 2008 Virologyjournal 2008 5 61 doi 10.1186 1743-422X-5-61 This article is available from http www.virologyj.cOm content 5 1 61 2008 van der Walt et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background A variety of interactions between up to three different movement proteins MPs the coat protein CP and genomic DNA mediate the inter- and intra-cellular movement of geminiviruses in the genus Begomovirus. Although movement of viruses in the genus Mastrevirus is less well characterized direct interactions between a single MP and the CP of these viruses is also clearly involved in both intra- and intercellular trafficking of virus genomic DNA. However it is currently unknown how specific these MP-CP interactions are nor how disruption of these interactions might impact on .