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báo cáo hóa học:" Multicistronic lentiviral vectors containing the FMDV 2A cleavage factor demonstrate robust expression of encoded genes at limiting MOI"

Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học đề tài :Multicistronic lentiviral vectors containing the FMDV 2A cleavage factor demonstrate robust expression of encoded genes at limiting MOI | Virology Journal BioMed Central Research Open Access Multicistronic lentiviral vectors containing the FMDV 2A cleavage factor demonstrate robust expression of encoded genes at limiting MOI Dhanalakshmi Chinnasamy1 Michael D Milsom2 5 James Shaffer1 James Neuenfeldt1 Aimen F Shaaban3 Geoffrey P Margison4 Leslie J Fairbairn2 and Nachimuthu Chinnasamy 1 Address 1Vince Lombardi Gene Therapy Laboratory Immunotherapy Program Aurora St. Luke s Medical Center 2900 West Oklahoma Avenue Milwaukee WI 53215 USA 2Cancer Research UK Gene Therapy Group Paterson Institute for Cancer Research Christie Hospital NHS Trust Wilmslow Road Manchester M20 4BX UK 3Surgery Department University of Wisconsin Madison WI 53792 USA 4Cancer Research UK Carcinogenesis Group Paterson Institute for Cancer Research Christie Hospital NHS Trust Wilmslow Road Manchester M20 4BX UK and 5Division of Experimental Hematology Cincinnati Children s Hospital Medical Center Cincinnati OH 45229 USA Email Dhanalakshmi Chinnasamy- dhana.chinnasamy@aurora.org Michael D Milsom - Michael.Milsom@cchmc.org James Shaffer - james.shaffer@aurora.org James Neuenfeldt - james.neuenfeldt@pcmail.maricopa.edu Aimen F Shaaban - Shaaban@surgery.wisc.edu Geoffrey P Margison - GMargison@PICR.man.ac.uk Leslie J Fairbairn - LFairbairn@PICR.man.ac.uk Nachimuthu Chinnasamy - samy.chinnasamy@aurora.org Corresponding author Published 15 March 2006 Received 13 December 2005 Accepted 15 March 2006 VirologyJournal2006 3 14 doi 10.1186 1743-422X-3-14 This article is available from http www.virologyj.cOm content 3 1 14 2006Chinnasamy et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background A number of gene therapy applications would benefit from vectors capable of expressing .