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báo cáo hóa học:" A ‘short walk’ is longer before radiotherapy than afterwards: a qualitative study questioning the baseline and follow-up design"

Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí hóa học đề tài : A ‘short walk’ is longer before radiotherapy than afterwards: a qualitative study questioning the baseline and follow-up design | Taminiau-Bloem et al. Health and Quality of Life Outcomes 2010 8 69 http www.hqlo.eom content 8 1 69 HEALTH AND QUALITY OF LIFE OUTCOMES RESEARCH Open Access A short walk is longer before radiotherapy than afterwards a qualitative study questioning the baseline and follow-up design Elsbeth F Taminiau-Bloem1 Florence J van Zuuren2t Margot A Koeneman1t Bruce D Rapkin3t Mechteld RM Visser4t Caro CE Koning5t Mirjam AG SprangersH Abstract Background Numerous studies have indirectly demonstrated changes in the content of respondents QoL appraisal process over time by revealing response-shift effects. This is the first known study to qualitatively examine the assumption of consistency in the content of the cognitive processes underlying QoL appraisal over time. Specific objectives are to examine whether the content of each distinct cognitive process underlying QoL appraisal is dis similar over time and whether patterns of dis similarity can be discerned across and within patients and or items. Methods We conducted cognitive think-aloud interviews with 50 cancer patients prior to and following radiotherapy to elicit cognitive processes underlying the assessment of 7 EORTC QLQ-C30 items. Qualitative analysis of patients responses at baseline and follow-up was independently carried out by 2 researchers by means of an analysis scheme based on the cognitive process models of Tourangeau et al. and Rapkin Schwartz. Results The interviews yielded 342 comparisons of baseline and follow-up responses which were analyzed according to the five cognitive processes underlying QoL appraisal. The content of comprehension frame of reference changed in 188 comparisons retrieval sampling strategy in 246 standards of comparison in 152 judgment combinatory algorithm in 113 and reporting and response selection in 141 comparisons. Overall in 322 comparisons of responses 94 the content of at least one cognitive component changed over time. We could not discern patterns of dis similarity since the