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báo cáo hóa học:" Respiratory symptoms in adults are related to impaired quality of life, regardless of asthma and COPD: results from the European community respiratory health survey"

Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí hóa học đề tài :Respiratory symptoms in adults are related to impaired quality of life, regardless of asthma and COPD: results from the European community respiratory health survey | Voll-Aanerud et al. Health and Quality of Life Outcomes 2010 8 107 http www.hqlo.eom content 8 1 107 HEALTH AND QUALITY of life outcomes RESEARCH Open Access Respiratory symptoms in adults are related to impaired quality of life regardless of asthma and COPD results from the European community respiratory health survey 1.2 13 2 1.4 13 1 Marianne Voll-Aanerud Tomas ML Eagan Estel Plana Ernst R Omenaas Per S Bakke Cecilie Svanes Valerie Siroux5 Isabelle Pin5 Josep M Antó2 6 Benedicte Leynaert7 Abstract Background Respiratory symptoms are common in the general population and their presence is related to Health-related quality of life HRQoL . The objective was to describe the association of respiratory symptoms with HRQoL in subjects with and without asthma or COPD and to investigate the role of atopy bronchial hyperresponsiveness BHR and lung function in HRQoL. Methods The European Community Respiratory Health Survey ECRHS I and II provided data on HRQoL lung function respiratory symptoms asthma atopy and BHR from 6009 subjects. Generic HRQoL was assessed through the physical component summary PCS score and the mental component summary MCS score of the SF-36. Factor analyses and linear regressions adjusted for age gender smoking occupation BMI comorbidity and study centre were conducted. Results Having breathlessness at rest in ECRHS II was associated with mean score 95 CI impairment in PCS of -8.05 -11.18 -4.93 . Impairment in MCS score in subjects waking up with chest tightness was -4.02 -5.51 -2.52 . The magnitude of HRQoL impairment associated with respiratory symptoms was similar for subjects with and without asthma COPD. Adjustments for atopy BHR and lung function did not explain the association of respiratory symptoms and HRQoL in subjects without asthma and or COPD. Conclusion Subjects with respiratory symptoms had poorer HRQoL including subjects without a diagnosis of asthma or COPD. These findings suggest that respiratory symptoms in the absence of a medical