Translational medicine refers to the process by which the results of research done in the laboratory are directly used to develop new ways to treat patients. It depends on the comprehensive integration of the entire breadth of patient data with basic life sciencedatatofacilitateandevaluatedrugdevelopment[2].Inthe1990s,several efforts related to data integration emerged, including the Archimedes Project and the use of heterogeneous data integration, mathematical and computational modeling, and simulation to expose the underlying dynamics and different individual treatment response patterns clinicians observed in patients diagnosed with Major Depressive Dis- order [7][8]. When information regarding the patient experience (symptoms, pharma- cokinetics/pharmacodynamics, outcomes, side effects) can be directly linked to biomedical knowledge (genetics, pathways, enzymes,.