DNA hypermethylation changes in CpG islands of promoter region of E-cadherin (E-cad) gene, one of the tumor suppressor genes, have been described to be involved the formation and progression of human nasopharyngeal carcinoma, which is the most common and highly incident cancer of head and neck cancer in Asian countries, especially in Vietnam. | In silico analysis of hypermethylation of E-cadherin gene promoter in nasopharyngeal carcinoma