A total of 150 samples from poultry were evaluated for avian pathogenic E. coli. All the 77 isolates of E. coli were tested for in vitro sensitivity towards 14 antibacterial drugs. The highest resistance was attributed towards antibiotic ampicillin, colistin, and nitrofurantoin followed by cefixime, cotrimoxazole, doxycycline, tetracycline, amoxyclav, ofloxacin, streptomycin, gentamicin, levofloxacin and amikacin. The highest sensitivity of E. coli was towards chloramphenicol antibiotic. Simultaneous resistance to 6 to 11 antibacterial agents was observed in all 77 (100%) isolates.
