Diabetes mellitus is a metabolic disorder characterized by hyperglycemia and alterations in carbohydrate, fat and protein metabolisms. Diabetes is associated with absolute or relative deficiencies in insulin secretion by pancreatic β-cells and/or insulin action. For the treatment of diabetes large numbers of herbal preparations are in vogue. Plant cells produced secondary metabolites which are biologically active constituents with therapeutic and prophylactic applications in humans. | Plant secondary metabolites of pharmacological significance in reference to diabetes mellitus An update