Bài viết Khảo sát tình hình sử dụng kháng sinh trong điều trị đợt cấp COPD tại bệnh viện 74 trung ương được nghiên cứu với mục tiêu khảo sát tình hình sử dụng kháng sinh ở bệnh nhân nhập viện điều trị đợt cấp COPD tại Bệnh viện 74 Trung ương. Dữ liệu thu thập được từ 265 bệnh nhân nhập viện trong giai đoạn 01/01/2021 - 31/03/2021. | VNU Journal of Science Medical and Pharmaceutical Sciences Vol. 38 No. 2 2022 56-64 Original Article A Survey of Antibiotic Usage Characteristics in Treatment of Acute Exacerbation of COPD Patients in National Hospital 74 Tran Xuan Bach1 Tran Thanh Trung1 2 Bui Son Nhat1 Le Thi Luyen1 1 VNU University of Medicine and Pharmacy 144 Xuan Thuy Cau Giay Hanoi Vietnam 2 National Hospital 74 Phuc Yen Vinh Phuc Vietnam Received 01 June 2022 Revised 08 June 2022 Accepted 08 June 2022 Abstract Acute exacerbation of COPD AECOPD represents a pivotal point in the progression of COPD which is a major cause of physician visits hospitalization and death in COPD patients. Bacterial respiratory infections have long been considered the main cause of exacerbations. This study was conducted with the aim of surveying the antibiotic usage characteristics in AECOPD of hospitalized patients at National Hospital 74. Data were collected from 265 patients hospitalized from January 1st 2021 to March 31st 2021. Most of the patients in the study were male and had comorbidities . The most isolated bacteria were Haemophilus influenzae Moraxella catarrhalis and Pseudomonas aeruginosa. The majority of patients did not change their antibiotic regimen during treatment . Alternative regimens in patients having regimen changes tended to be more focused on Pseudomonas aeruginosa than the first regimens. In the antibiotic-containing regimens tested antibiograms of 38 patients with isolated bacteria most of the regimens had at least 1 antibiotic sensitive to the isolated bacteria . The results of this study provide reliable information for making recommendations to contribute to improving the effectiveness of antibiotic usage in the AECOPD treatment at National Hospital 74 reducing the medical burden for patients and society. Keywords COPD acute exacerbation antibiotics. _ Corresponding author. E-mail address luyenle66@ https 2588-1132 56 T. X. .
