Ebook "Using mass spectrometry for biochemical studies on enzymatic domains from polyketide synthases" reports studies on the substrate specificity of crucial KS domains from trans-AT PKSs. Using a combination of electrospray ionisation-mass spectrometry (ESI-MS) and simple N-acetyl cysteamine (SNAC) substrate mimics, the substrate specificity of a range of KS domains from the bacillaene (BaeJ and BaeL) and psymberin (PsyA and PsyD) PKSs, . |