Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Do methadone and buprenorphine have the same impact on psychopathological symptoms of heroin addicts? | Maremmani et al. Annals of General Psychiatry 2011 10 17 http content 10 1 17 ANNALS OF GENERAL PSYCHIATRY PRIMARY RESEARCH Open Access Do methadone and buprenorphine have the same impact on psychopathological symptoms of heroin addicts Ạ nncilrì lr rm K loiromm1 2 3 I I ir i Dr A Tii 1 Dior Dtrni4 l loftQOi Dsir ir ii1 3 rrnnr-Qcrri I m nn 5 Algelo Giovdlli Icro IVIdlclllllldlll Lucd Rovdi riel Pdolo Pdli IVIdLLcU Pdcili rldlicescu Ldllldlllld Fabio Rugdni1 Elisd Schidvi1 Lilidld Dell Osso1 dnd Icro Mdremmdli1 2 3 Abstract Background The ided thdt the impdct of opioid dgolist tredtmelt is ilfluelced by the psychopathological profile of heroil dddicts hds lot yet beel investigated dld is bdsed ol the colcept of d specific therapeutic dctiol displdyed by opioid dgelts ol psychopathological symptoms. Il the preselt report we compdred the effects of buprelorphile dld methddole ol the psychopathological symptoms of 213 pdtielts 106 ol buprelorphile dld 107 ol methddole il d follow-up study ldstilg 12 molths. Methods Drug addictiol history wds collected by medls of the Drug Addictiol History Rdtilg Scdle DAH-RS dld psychopathological fedtures were collected by medls of the Symptom Checklist-90 SCL-90 usilg d specidl five-fdctor solutiol. Toxicologicdl urildlyses were cdrried out for edch pdtielt durilg the tredtmelt period. Results No stdtisticdlly siglificdlt differelces were detected il psychopdthologicdl symptoms ilcludilg worthlessless-beilg trapped somdtizdtiol dld pdlic-dlxiety . Methddole proved to be more effective ol pdtielts characterized by selsitivity-psychoticism whereds buprelorphile wds more effective ol pdtielts displdyilg d violelce-suicide symptomdtology. Conclusions Heroil-depeldelt pdtielts with psychidtric comorbidities mdy belefit from opioid dgolist tredtmelt lot olly becduse it tdrgets their dddictive problem but dlso precisely due to this becduse it is effective dgdilst their meltdl disorder too. Background .
