Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Osteoarthritis and nutrition. From nutraceuticals to functional foods: a systematic review of the scientific evidence. | Available online http content 8 4 R1 27 Research article Osteoarthritis and nutrition. From nutraceuticals to functional foods a systematic review of the scientific evidence Laurent G Ameye and Winnie SS Chee Nutrition and Health Department Nestlé Research Center Vers-chez-les-Blanc 1000 Lausanne 26 Switzerland Corresponding author Laurent G Ameye Received 4 Jan 2006 Revisions requested 16 Mar 2006 Revisions received 6 Jun 2006 Accepted 19 Jul 2006 Published 19 Jul 2006 Arthritis Research Therapy 2006 8 R127 doi ar2016 This article is online at http content 8 4 R1 27 2006 Ameye and Chee licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract The scientific and medical community remains skeptical regarding the efficacy of nutrition for osteoarthritis despite their broad acceptation by patients. In this context this paper systematically reviews human clinical trials evaluating the effects of nutritional compounds on osteoarthritis. We searched the Medline Embase and Biosis databases from their inception to September 2005 using the terms random double-blind method trial study placebo and osteoarthritis. We selected all peer-reviewed articles reporting the results of randomised human clinical trials RCTs in osteoarthritis that investigated the effects of oral interventions based on natural molecules. Studies on glucosamine and chondroitin sulfate were excluded. The quality of the RCTs was assessed with an osteoarthritic-specific standardised set of 12 criteria and a validated instrument. A best-evidence synthesis was used to categorise the scientific evidence behind each nutritional compound as good moderate or limited. A summary of
