Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: Pharmacological inhibition of leukotrienes in an animal model of bleomycin-induced acute lung injury. | Respiratory Research BioMed Central Open Access Pharmacological inhibition of leukotrienes in an animal model of bleomycin-induced acute lung injury Marco Failla41 Tiziana Genovese42 3 Emanuela Mazzon2 3 Elisa Gili1 Carmelo Muià2 3 Mariangela Sortino4 Nunzio Crimi1 Achille P Caputi2 3 Salvatore Cuzzocrea42 3 and Carlo Vancheri 1 Address Department of Internal Medicine and Specialistic Medicine Section of Respiratory Diseases University of Catania Catania Italy 2Department of Clinical and Experimental Medicine and Pharmacology University of Messina Messina Italy 3Centro per lo Studio e il Trattamento dei Neurolesi Lungodegenti University of Messina Messina Italy and 4Department of Clinical and Experimental Medicine and Pharmacology Catania Italy Email Marco Failla - marcofailla@ Tiziana Genovese - genovese@ Emanuela Mazzon - mazzon@ Elisa Gili - elisagili@ Carmelo Muià - muia@ Mariangela Sortino - Sortino@ Nunzio Crimi - crimi@ Achille P Caputi - caputi@ Salvatore Cuzzocrea - salvator@ Carlo Vancheri - vancheri@ Corresponding author fEqual contributors Published 21 November 2006 Received 12 July 2006 n nnrnz J. .IA IIOZM jzr ooin m Accepted 21 November 2006 Respiratory Research 2006 7 137 doi 1465-9921-7-137 This article is available from http content 7 1 137 2006 Failla et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Leukotrienes are increased locally in idiopathic pulmonary fibrosis. Furthermore a role for these arachidonic acid metabolites has been thoroughly characterized in the animal bleomycin model of lung fibrosis by using different gene knock-out settings. We investigated
