Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: "Altered expression of membrane-bound and soluble CD95/Fas contributes to the resistance of fibrotic lung fibroblasts to FasL induced apoptosis. | Respiratory Research BioMed Central Research Open Access Altered expression of membrane-bound and soluble CD95 Fas contributes to the resistance of fibrotic lung fibroblasts to FasL induced apoptosis Frank Buhling 1 6 Aline Wille1 2 Christoph Rocken3 Olaf Wiesner4 Anja Baier2 Ingmar Meinecke2 5 Tobias Welte4 and Thomas Pap2 5 Address 1Institute of Immunology Otto-von-Guericke-University Magdeburg Germany 2Division of Experimental Rheumatology Otto-von-Guericke-University Magdeburg Germany institute of Pathology Otto-von-Guericke-University Magdeburg Germany 4Department of Pneumology Hannover Medical School Hannover Germany 5Division of Molecular Medicine of Musculoskeletal Tissue University Hospital Munster Germany and institute of Clinical Chemistry and Laboratoy Diagnostics Carl-Thiem-Klinikum Cottbus gGmbH Thiemstr. 111 03048 Cottbus Germany Email Frank Buhling - frank@ Aline Wille - Christoph Rocken - Olaf Wiesner - Anja Baier - Ingmar Meinecke - Tobias Welte - Thomas Pap - Corresponding author Published 17 April 2005 Received 01 November 2004 Respiratory Research 2005 6 37 doi 1465-9921 -6-37 Accepted 17 April 2005 This article is available from http content 6 1 37 2005 Buhling et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background An altered susceptibility of lung fibroblasts to Fas-induced apoptosis has been implicated in the pathogenesis of pulmonary fibrosis however the underlying mechanism is not completely understood. Here we