Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Cardiac troponin level is not an independent predictor of mortality in septic patients requiring medical intensive care unit admission. | Available online http content 10 1 404 Letter Cardiac troponin level is not an independent predictor of mortality in septic patients requiring medical intensive care unit admission Franọois G Brivet1 Frédéric M Jacobs1 Patrice Colin2 Dominique Prat1 and Bogdan Grigoriu1 1 Medical Intensive Care Unit - Hôpital Antoine Béclère Assistance Publique-Hôpitaux de Paris France 2Cardiologic Department - Hôpital Antoine Béclère Assistance Publique-Hôpitaux de Paris and Paris XI University Paris France Corresponding author Franọois G Brivet Published 2 February 2006 Critical Care 2006 10 404 doi cc3990 This article is online at http content 10 1 404 2006 BioMed Central Ltd See related letter by Turley and Gedney in issue http content 9 6 E30 and related research by King et al. in issue http content 9 4 R390 and Lim et al. in issue http content 9 6 R636 Turley and Gedney claim that the cardiac troponin Ic level is a predictor of adverse outcome 1 and that their results support those of King and colleagues 2 . Unfortunately King and colleagues were unable to demonstrate a link between the troponin Ic level and mortality when using a multivariate model including the Acute Physiology Age and Chronic Health Evaluation II score. Interpretation of the results of Turley and Gedney therefore requires caution since their results are based only on univariate analysis 1 . We prospectively evaluated the accuracy of cardiac troponin Ic levels to predict inhospital mortality in 118 adults with documented sepsis and no history of cardiac arrest or acute coronary syndrome and we then compared this accuracy with the performance of the new Simplified Acute Physiology II score. Seventy-five patients were in shock systolic blood pressure 90 mmHg while 58 patients 49 had a cardiac troponin Ic level greater than ng ml detection limit ng ml and 43 patients a level greater .
