Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care cung cấp cho các bạn kiến thức về ngành y đề tài: Intensive care acquired infection is an independent risk factor for hospital mortality: a prospective cohort study. | Available online http content 10 2 R66 Research Intensive care acquired infection is an independent risk factor for hospital mortality a prospective cohort study Pekka Ylipalosaari1 Tero I Ala-Kokko2 Jouko Laurila2 Pasi Ohtonen3 and Hannu Syrjala1 Department of Infection Control Oulu University Hospital FIN-90029 OYS Finland 2Department of Anesthesiology Division of Intensive Care Oulu University Hospital FIN-90029 OYS Finland 3Departments of Anesthesiology and Surgery Oulu University Hospital FIN-90029 OYS Finland Corresponding author Pekka Ylipalosaari Received 14 Dec 2005 Revisions requested 13 Feb 2006 Revisions received 7 Mar 2006 Accepted 23 Mar 2006 Published 20 Apr 2006 Critical Care 2006 10 R66 doi cc4902 This article is online at http content 10 2 R66 2006 Ylipalosaari et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction The aim of this study was to elucidate the impact of intensive care unit ICU -acquired infection on hospital mortality. Methods Patients with a longer than 48 hour stay in a mixed 10 bed ICU in a tertiary-level teaching hospital were prospectively enrolled between May 2002 and June 2003. Risk factors for hospital mortality were analyzed with a logistic regression model. Results Of 335 patients 80 developed ICU-acquired infection. Among the patients with ICU-acquired infections hospital mortality was always higher regardless of whether or not the patients had had infection on admission infection on admission group IAG versus 17 p and no-IAG versus p . In IAG n 251 hospital stay was also longer in the presence of ICU-acquired infection median 31 versus 16 days p whereas in .