Bài viết Nghiên cứu một số yếu tố liên quan động kinh kháng thuốc trẻ em tại Nghệ An trình bày việc xác định các yếu tố liên quan động kinh kháng thuốc, từ đó định hướng, cách tiếp cận điều trị thích hợp hơn cho bệnh nhân động kinh tại Việt Nam. | Vietnam Journal of Community Medicine Vol. 65 No. 1 87-93 INSTITUTE OF COMMUNITY HEALTH ANALYSIS OF SOME RISK FACTORS ASSOCIATED WITH DRUG-RESISTANT EPILEPSY IN CHILDREN Tang Xuan Hai Ho Dang Muoi Nguyen Van Ngoc Nghe An Obstetrics and Pediatrics Hospital - 19 Ton That Tung Hung Dung Vinh City Nghe An Vietnam Received 28 09 2023 Revised 11 11 2023 Accepted 14 12 2023 ABSTRACT Objective Identify some risk factors for drug-resistant epilepsy in children. Subjects and methods Cross-sectional descriptive study on 100 children with epilepsy. including 46 females 46 and 54 males 54 divided into 2 groups drug-resistant epilepsy group n 50 and drug-responsive epilepsy group n 50 diagnostic criteria according to the International Association against Epilepsy ILAE 2010 . Results Drug-resistant epilepsy with a history of status epilepticus accounted for 30 neonatal seizures accounted for 22 febrile seizures accounted for 44 psychomotor retardation accounted for 92 . The average age of onset in the drug-resistant epilepsy group was 13 months the average frequency of seizures per day was 12 8. Generalized epilepsy accounted for 74 of both study groups. There were 18 cases classified as syndrome accounting for 18 . Paraclinical results of electrostatic discharge and brain MRI were abnormal in drug-resistant and responsive epilepsy groups accounting for 94 and 30 respectively. Regression analysis of results Neonatal seizures febrile seizures history of status epilepticus delayed psychomotor development abnormal electroencephalogram and MRI are factors related to epilepsy. Conclusion Patients with a history of neonatal seizures a history of febrile seizures a history of status epilepticus psychomotor retardation abnormal electroencephalogram and brain MRI are risk factors. associated with drug-resistant epilepsy. Keywords Children epilepsy drug-resistant epilepsy. Corressponding author Email address bstangxuanhai@ Phone number 84 912 379 583 https .
