Dendritic cells (DCs) alter their role from being immunostimulatory to immunosuppressive at advanced stages of tumor progression, but the influence of cancer stem cells (CSCs) and their secreted factors on generation and phenotypic change of DCs is unknown. | Induction of tolerogenic dendritic cells by activated TGF-β Akt Smad2 signaling in RIG-I-deficient stemness-high human liver cancer cells