Bài viết trình bày đánh giá hiệu quả giảm đau sau mổ của magie sulfat đường tĩnh mạch kết hợp với gây tê tủy sống bằng hỗn hợp bupivacain - fentanyl trong mổ lấy thai và các tác dụng không mong muốn của phương pháp. | Vietnam Journal of Community Medicine Vol. 64 Special Issue 11 72-78 RESEARCH ON THE EFFECTIVENESS OF POSTOPERATIVE ANALGESIA WITH IV MAGNESIUM SULFATE COMBINED WITH SPINAL ANESTHESIA IN CESAREAN SECTION Dao Van Cuong1 Tran Dac Tiep2 Nguyen Ngoc Thach2 Nguyen Van Quynh3 1 Son Tay General Hospital - Le Loi Street Le Loi Ward Son Tay Hanoi Vietnam 2 Military Hospital 103 - 261 Phung Hung Street Ha Dong Hanoi Vietnam 3 National Burn Hospital - 263 Phung Hung Street Ha Dong Hanoi Vietnam Received 14 09 2023 Revised 03 10 2023 Accepted 31 10 2023 ABSTRACT Objectives To evaluate the effectiveness of postoperative analgesia with IV magnesium sulfate in combination with spinal anesthesia with a bupivacaine-fentanyl mixture in cesarean section and unwanted effects of the method. Subjects and methods 80 pregnant ages 18 and over with ASA I or II and indications for cesarean section under spinal anesthesia were divided into 2 groups each of which contained 40 women. Group 1 study group Spinal anesthesia with 7 mg bupivacaine and 25 mcg fentanyl. Thereafter 250 mg of magnesium sulfate was given intravenously followed by an infusion of 500 mg of magnesium sulfate 25 mg mL at a rate of 20 mL hour. Group 2 control group Spinal anesthesia with 7mg bupivacaine and 25 mcg fentanyl. Then intravenously inject ml of NaCl solution followed by 20 ml of NaCl solution at a rate of 20 ml hour. In the postoperative room when the woman has a VAS score 4 inject 1 mg of morphine intravenously reassess after 3 minutes if the VAS score is still 4 inject 1 mg of intravenous morphine every 3 minutes until the VAS score lt 4 the total loading dose of morphine lt 10 mg. Then maintain a continuous infusion of morphine at 1 mg hour by pump syringe. Results The postoperative analgesia duration of the group 1 minutes was longer than that of the group 2 minutes p lt . The effective analgesia duration of the group 1 10 98 minutes was longer than .
