Bài viết Mối liên quan giữa nồng độ acid uric và một số đặc điểm lâm sàng, cận lâm sàng trên bệnh nhân tiền sản giật được nghiên cứu với mục tiêu: Khảo sát mối liên quan giữa nồng độ acid uric và đặc điểm lâm sàng, cận lâm sàng trên bệnh nhân tiền sản giật. | Vietnam Journal of Community Medicine Vol. 64 Special Issue 9 2023 181-188 INSTITUTE OF COMMUNITY HEALTH THE CORRELATION BETWEEN URIC ACID WITH THE CHARACTERISTICS OF CLINICAL SUBCLINICAL IN PRE-ECLAMPSIA Nguyen Anh Thu1 Le Thi Minh Hien1 Do Thai Phuong2 Pham Thi Thanh Thuy3 Ngo Vu Thuy Trang1 1 Thai Nguyen University of Medicine and Pharmacy - 284 Luong Ngoc Quyen Quang Trung Thai Nguyen City Thai Nguyen Vietnam 2 A Thai Nguyen Hospital - Thinh Dan Thai Nguyen City Thai Nguyen Vietnam 3 National Hospital of Obstetrics and Gynecology - 43 Trang Thi Hoan Kiem Hanoi Vietnam Received 18 07 2023 Revised 14 08 2023 Accepted 23 09 2023 ABSTRACT Objectives To investigate the correlation between serum uric acid with the characteristics of clinical subclinical in pre-eclampsia. Methods Three groups of pregnant women including 33 pregnant women at risk of pre- eclampsia 25 patients with mild preeclampsia and 13 patients with severe preeclampsia from 1st Wednesday 2023 to September 2023 at A Thai Nguyen Hospital. Blood uric acid was de- termined by the method of hydrolysis of uricase enzyme and measured at the optical density at 505 nm. Results The average concentrations of uric acid in the patients at risk of preeclampsia mild preeclampsia and severe preeclampsia groups were 429 66 81 50 µmol L 466 39 56 12 µmol L and 534 17 68 54 µmol L respectively the concentration of uric acid of severe pre- eclampsia group is higher than that of the two groups p lt 0 001 . There is a correlation between serum uric acid and serum urea creatinin AST ALT protein albumin and proteinuria in three groups. Conclusion The concentration of uric acid of severe preeclampsia group is higher than that of the patients at risk of preeclampsia and mild preeclampsia group. The concentration of uric acid is correlated with biochemical indicators including urea creatinin AST ALT protein albumin and proteinuria in group of research subjects. Keywords Pre-eclampsia Uric Acid. Corressponding author Email .
