Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Psychosocial functioning in patients with treatment-resistant depression after group cognitive behavioral therapy | Matsunaga et al. BMC Psychiatry 2010 10 22 http 1471-244X 10 22 BMC Psychiatry RESEARCH ARTICLE Open Access Psychosocial functioning in patients with treatment-resistant depression after group cognitive behavioral therapy Ỷ 1Ỷ 3Ỷ 1Ỷ 1Ỷ Miki Matsunaga Yasumasa Okamoto Shin-ichi Suzuki Akiko Kinoshita Shinpei Yoshimura Atsuo Yoshino1Ỷ Yoshihiko Kunisato1Ỷ Shigeto Yamawaki1 Abstract Background Although patients with Treatment Resistant Depression TRD often have impaired social functioning few studies have investigated the effectiveness of psychosocial treatment for these patients. We examined whether adding group cognitive behavioral therapy group-CBT to medication would improve both the depressive symptoms and the social functioning of patient with mild TRD and whether any improvements would be maintained over one year. Methods Forty-three patients with TRD were treated with 12 weekly sessions of group-CBT. Patients were assessed with the Global Assessment of Functioning scale GAF the 36-item Short-Form Health Survey SF-36 the Hamilton Rating Scale for Depression HRSD the Dysfunctional Attitudes Scale DAS and the Automatic Thought Questionnaire-Revised ATQ-R at baseline at the termination of treatment and at the 12-month follow-up. Results Thirty-eight patients completed treatment five dropped out. For the patients who completed treatment post-treatment scores on the GAF and SF-36 were significantly higher than baseline scores. Scores on the HRSD DAS and ATQ-R were significantly lower after the treatment. Thus patients improved on all measurements of psychosocial functioning and mood symptoms. Twenty patients participated in the 12-month follow-up. Their improvements for psychosocial functioning depressive symptoms and dysfunctional cognitions were sustained at 12 months following the completion of group-CBT. Conclusions These findings suggest a positive effect that the addition of cognitive behavioural group therapy to medication on .