Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Mixed states vs. pure mania in the french sample of the EMBLEM study: results at baseline and 24 months – European mania in bipolar longitudinal evaluation of medication | BMC Psychiatry BioMed Central Open Access Research article Mixed states vs. pure mania in the french sample of the EMBLEM study results at baseline and 24 months - European mania in bipolar longitudinal evaluation of medication Jean-Michel Azorin1 Elodie Aubrun2 Jordan Bertsch3 Catherine Reed4 Stephanie Gerard2 and Michael Lukasiewicz 2 Address 1SHU psychiatrie adulte CHU Ste Margueritte Marseille France 2Neurosciences Medical department Eli Lilly and company Suresnes France 3Fundacio Sant Joan de Déu Serveis de Salut Mental Hospital Sant Joan de Déu Barcelona Spain and 4European Health Outcomes Eli Lilly and company Windlesham UK Email Jean-Michel Azorin - ajazorin@ Elodie Aubrun - aubrunelodie@ Jordan Bertsch - jbertsch@ Catherine Reed - reed_catherine@ Stephanie Gerard - gerardst@ Michael Lukasiewicz - lukasiewicz_michael@ Corresponding author Published 7 June 2009 Received 29 October 2008 BMC Psychiatry 2009 9 33 doi 1471-244X-9-33 Accepted 7 June 2009 This article is available from http 1471-244X 9 33 2009 Azorin et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background To describe the clinical course and treatment patterns over 24 months of patients experiencing an acute manic mixed episode within the standard course of care. Methods EMBLEM was a 2-year European prospective observational study on outcomes of patients experiencing a manic mixed episode. Adults with bipolar disorder were enrolled within the standard course of care as in outpatients if they initiated or changed oral medication for treatment of acute mania. After completing 12 weeks of acute phase patients were assessed every 3-6 months during the .