Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: A hypothetical correlation between hyaluronic acid gel and development of cutaneous metaplastic synovial cyst | Inchingolo et al. Head Face Medicine 2010 6 13 http content 6 1 13 HEAD FACE MEDICINE HYPOTHESIS Open Access Aphyplothetical correlation between hyaluronic acid gel and development of cutaneous metaplastic synovial cyst Francesco Inchingolo 1 Marco Tatullo2 Fabio M Abenavoli3 Massimo Marrelli4 Alessio D Inchingolo5 Andrea Servili6 Angelo M Inchingolo7 and Gianna Dipalma8 Abstract Thousands of patients receive hyaluronic acid filler injections and the effects are generally considered acceptable. The acid rarely causes cutaneous reactions which are only occasionally reported in the literature. The aim of the present work is to analyze a clinical case that has never been reported in the literature to our knowledge. This case is of a 26-year-old woman who presented with a cyst in the infrazygomatic region that was injected with non-animal stabilized hyaluronic acid at another centre a few months ago. Consequently we made an external incision to remove the neoplasm histological examination of the capsule revealed it to be a cutaneous metaplastic synovial cyst. Introduction Thousands of patients receive hyaluronic acid filler injections the effects of which are generally considered acceptable. However in all cases the product is regarded as resorbable and the risk of either local or systemic toxic reactions is reduced 1 2 . Hyaluronic acid should be administered with caution like any type of commonly employed dermal fillers but the injection technique can be easily performed after a brief learning course. The acid rarely causes cutaneous reactions which are reported only occasionally in the literature. Case Report The aim of the present work is to analyze a clinical case that has never been reported in the literature to our knowledge. This case is of a 26-year-old woman who presented with a cyst in the infrazygomatic region FIG. 1 that was injected with non-animal stabilized hyaluronic acid NASHA at another centre a few months ago. The patient did .