Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Preoperative Y-90 microsphere selective internal radiation treatment for tumor downsizing and future liver remnant recruitment: a novel approach to improving the safety of major hepatic resections | BioMed Central World Journal of Surgical Oncology Open Access Preoperative Y-90 microsphere selective internal radiation treatment for tumor downsizing and future liver remnant recruitment a novel approach to improving the safety of major hepatic resections Seza A Gulec 1 3 Kenneth Pennington1 Michael Hall1 and Yuman Fong2 Address 1Center for Cancer Care at Goshen Health System Goshen IN USA 2Memorial Sloan-Kettering Cancer Center New York NY USA and 3Current address Florida International University College of Medicine Miami FL 33199 USA Email Seza AGulec - sgulec@ Kenneth Pennington - kpennington@ Michael Hall - micjhall@ Yuman Fong - fongy@ Corresponding author Published 8 January 2009 Received 21 May 2008 World Journal of Surgical Oncology 2009 7 6 doi l477-78l9-7-6 Accepted 8 January 2009 This article is available from http content 7 l 6 2009 Gulec et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Extended liver resections are being performed more liberally than ever. The extent of resection of liver metastases however is restricted by the volume of the future liver remnant FLR . An intervention that would both accomplish tumor control and induce compensatory hypertrophy with good patient tolerability could improve clinical outcomes. Case presentation A 53-year-old woman with a history of cervical cancer presented with a large liver mass. Subsequent biopsy indicated poorly differentiated carcinoma with necrosis suggestive of squamous cell origin. A decision was made to proceed with pre-operative chemotherapy and Y-90 microsphere SIRT with the intent to obtain systemic control over the disease downsize the hepatic lesion and improve .
