Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: An ultrasonographic evaluation of skin thickness in breast cancer patients after postmastectomy radiation therapy. | Wong et al. Radiation Oncology 2011 6 9 http content 6 1 9 RADIATION ONCOLOGY RESEARCH Open Access An ultrasonographic evaluation of skin thickness in breast cancer patients after postmastectomy radiation therapy r A 1 2 A IV -X I I 2 u Iz3 Id -X I A I I I -x -x4 c b I I D -X S S -X r I X I4 I I -X d r í I -X ỉ I I I 1 4 Sharon Wong Amarjit Kaur Michael Back Ixnai Mun Lee Shaun Baggarley Jiade Jay Lu Abstract Background To determine the usefulness of ultrasonography in the assessment of post radiotherapy skin changes in postmastectomy breast cancer patients. Methods Patients treated for postmastectomy radiotherapy in National University Hospital NUH and Tan Tock Seng Hospital TTSH Singapore between January 2004- December 2005 was recruited retrospectively. Ultrasound scan was performed on these Asian patients who had been treated to a total dose of 46-50 Gy with 1 cm bolus placed on the skin. The ultrasound scans were performed blinded to the RTOG scores and the skin thickness of the individually marked points on the irradiated chest wall was compared to the corresponding points on the nonirradiated breast. Results The mean total skin thickness inclusive of the epidermis and the dermis of the right irradiated chest wall was mm mm compared with the contra-lateral non-irradiated breast which was mm mm p . The left irradiated chest wall had a mean skin thickness of mm mm compared with the right non-irradiated breast which was mm mm p . These independent t-tests produced a significant difference of reduced skin thickness on the right irradiated chest wall p p and left irradiated chest wall p p in comparison to the non-irradiated skin thickness investigating chronic skin reactions. Patients with grade 2 acute skin toxicity presented with thinner skin as compared to patients with grade 1 p . Conclusions This study has shown that there is a statistically
