Bài viết trình bày đánh giá tác dụng ức chế tăng sinh lành tính tuyến tiền liệt của viên hoàn “TLT-BCA” trên chuột cống trắng gây tăng sản lành tính tuyến tiền liệt bằng testosterone propionate (TP). | Vietnam Journal of Community Medicine Vol. 65 No. 2 210-217 INSTITUTE OF COMMUNITY HEALTH THE EFFECT OF INHIBITING BENIGN PROSTATIC HYPERPLASIA OF TLT-BCA PILLS ON EXPERIMENT Nguyen Duy Hoan1 2 Pham Ba Tuyen2 Nguyen Truong Nam1 3 Nguyen Thi Lien1 4 1 Vietnam University Of Traditional Medicine amp Pharmacy - No. 2 Tran Phu Ha Dong Hanoi Vietnam Traditional Medicine Hospital Ministry of Public Security - 278 Luong The Vinh Trung Van Nam Tu Liem 2 Hanoi Vietnam 3 Phenikaa University - Nguyen Trac Yen Nghia Ha Dong Hanoi Vietnam 4 Rang Dong light source and vacuum flask joint stock Company - No. 87 - 89 Ha Dinh Thanh Xuan Trung Thanh Xuan Hanoi Vietnam Received 28 11 2023 Revised 27 12 2023 Accepted 19 02 2024 ABSTRACT Objectives To evaluate the effect of TLT-BCA pills on inhibiting benign prostatic hyperplasia induced by testosterone propionate TP in Wistar rats. Subjects and methods Wistar rats were injected subcutaneously with TP at a dose of 3mg kg 24h or with sesame oil physiological control group and given TLT-BCA treatment 1 and 2 groups Dutasteride reference group or physiological saline physiological control and pathological control groups for 28 consecutive days. Results TLT-BCA pills at dose 700mg kg 24h and 2100mg kg 24h reduced prostate weight decreased MDA concentration in both blood and prostate tissue of rats p lt compared to the pathology . Conclusions TLT-BCA pills have reduced prostate weight on the model of benign prostatic hyperplasia in Wistar rats. The mechanism of action may be involved in the antioxidant effects. Keywords Benign prostatic hyperplasia wistar rat TLT-BCA . Corressponding author Email address nguyenduyhoan8x@ Phone number 84 975 451 828 https 210 . Hoan et al. Vietnam Journal of Community Medicine Vol. 65 No. 2 210-217 TÁC DỤNG ỨC CHẾ TĂNG SINH LÀNH TÍNH TUYẾN TIỀN LIỆT CỦA VIÊN HOÀN CỨNG TLT-BCA TRÊN THỰC NGHIỆM Nguyễn Duy Hoàn1 2 Phạm Bá Tuyến2 Nguyễn Trường Nam1 3 Nguyễn Thị .
